Bone Abstracts

The balance of phosphate handling is now realized to occur through endocrine communication between the skeleton and kidneys. Low serum phosphate leads to severe growth plate defects, whereas elevated serum phosphate results in ectopic calcification of the vasculature and soft tissues. Mendelian disorders and their orthologous mouse models involving defects of growth plate formation and of calcinosis have brought to light new and important information regarding bone formation a...

Biographical DetailsKen White, PhD is the David D Weaver Professor of Genetics in the Department of Medical and Molecular Genetics at the Indiana University School of Medicine in Indianapolis, IN, USA. He serves as Director of the Division of Molecular Genetics and Gene Therapy. Dr K White’s research interests focus on the molecular genetics of metabolic bone diseases in regards to p...